Category Tau

The fibrosed and dysfunctional GIT prospects to reflux of gastric acid contents into the esophagus, a dilated and non compliant stomach, overgrowth of bacteria in the small intestine, colonic dilatation and a non-functional internal anal sphincter, alterations that manifest clinically as Barretts esophagus, gastroparesis, severe malabsorption, and fecal incontinence, respectively

The fibrosed and dysfunctional GIT prospects to reflux of gastric acid contents into the esophagus, a dilated and non compliant stomach, overgrowth of bacteria in the small intestine, colonic dilatation and a non-functional internal anal sphincter, alterations that manifest clinically…

Moreover, the myotonic-dystrophy-like phenotype of mice expressing (CUG)can be reversed by overproduction of MBNL1,9 and long-term MBNL1 overexpression prevents CUG-induced myotonia, myopathy and alternate splicing abnormalities in DM1 mice

Moreover, the myotonic-dystrophy-like phenotype of mice expressing (CUG)can be reversed by overproduction of MBNL1,9 and long-term MBNL1 overexpression prevents CUG-induced myotonia, myopathy and alternate splicing abnormalities in DM1 mice.10 PFI-1 MBNL1 is also sufficient to largely abolish DM1 foci gene…

Hensle, and B

Hensle, and B. global gene appearance evaluation in neuroblastoma cells constructed expressing the E proteins E47 and Identification2 acutely, we find that is clearly a focus on of E47. In keeping with the function of Id protein, Id2 stops activation…