In the oxidation direction the Tyr companions using the adjacent Lys residue to create TyrO? (phenolate anion) for proton abstraction through the steroid alcohol, Structure 6
In the oxidation direction the Tyr companions using the adjacent Lys residue to create TyrO? (phenolate anion) for proton abstraction through the steroid alcohol, Structure 6. from AKRs using the Tyr, Lys, Ser from SDRs [53]. This resulted in the…