Treatment of cells with antibodies to ICAM-1 or targeting ICAM-1 in mice significantly inhibits RSV disease and the production of inflammatory mediators, suggesting a therapeutic potential of anti-ICAM-1 methods; (2) intranasal administration in mice of a plasmid encoding IFN- significantly decreases viral replication in the mouse lung and reduces lung inflammation
Treatment of cells with antibodies to ICAM-1 or targeting ICAM-1 in mice significantly inhibits RSV disease and the production of inflammatory mediators, suggesting a therapeutic potential of anti-ICAM-1 methods; (2) intranasal administration in mice of a plasmid encoding IFN- significantly…