Our hypothesis explaining this behavior is that this elevated [Ca2+]i has reduced the Ca2+ sensitivity of the SMCs to almost 0 because of an increase in myosin light chain phosphatase (MLCP) activity
Our hypothesis explaining this behavior is that this elevated [Ca2+]i has reduced the Ca2+ sensitivity of the SMCs to almost 0 because of an increase in myosin light chain phosphatase (MLCP) activity. Airway relaxation induced by NOC-5 was accompanied by…